AZATHIOPRINE (has an active metabolite) | AZATHIOPRINE | ATC L04AX01
ANTINEOPLASTIC IMMUNOSUPPRESSIVE ANTIMETABOLITES ANTIRHEUMATIC AGENTS AZATHIOPRINE IS METABOLIZED TO 6-MERCAPTOPURINE (6-MP) AND THEN BY HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (HGPRT) AND DIVERSES KINASES WHICH LEAD TO THE INCORPORATION OF 6-THIOGUANINE NUCLEOTIDES (6-TGN) INTO DNA | ORAL INJECTION | Tmax 1.5 HOUR PPB 30 PERCENT SOLUBILITY INSOLUBLE IN WATER | DNA | Unknown more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |