ELAFIBRANOR (has an active metabolite) ![](https://chemoinfo.ipmc.cnrs.fr/TMP/tmp.67544/img_2115_mol.png)
| ELAFIBRANOR | ATC A05AX06
METABOLISM PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) PPAR-ALPHA, PPAR-GAMMA, AND PPAR-DELTA AGONIST TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) | ORAL | Cmax 2.08 MICROMOLAR Tmax 1.25 HOUR VD 4731 LITER PPB 99.7 PERCENT Cl 50.0 LITER / HOUR HT 70.2 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE AT PH 7.5 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) PDB 8HUQ (X-RAY STRUCTURE OF HUMAN PPAR ALPHA LIGAND BINDING DOMAIN-ELAFIBRANOR-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY SOAKING) LIGAND CODE = MUO (link to the list of PDB complexes) Download experimental 3D coordinates of MUO with added hydrogens | - more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |
M ELAFIBRANOR (is an active metabolite) ![](https://chemoinfo.ipmc.cnrs.fr/TMP/tmp.67544/img_2118_mol.png)
| ELAFIBRANOR | ATC A05AX06
METABOLISM PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) PPAR-ALPHA, PPAR-GAMMA, AND PPAR-DELTA AGONIST TREATMENT OF PRIMARY BILIARY CHOLANGITIS (PBC) | - | Cmax 5.35 MICROMOLAR PPB 99.7 PERCENT HT 15.4 HOUR | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) | - more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |