TEMSAVIR (is an active metabolite) | TEMSAVIR | ATC J05AX29
ANTIINFECTIVES A HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) GP120-DIRECTED ATTACHMENT INHIBITOR ANTIRETROVIRAL | - | Cmax 3.74 MICROMOLAR Tmax 2 HOUR F 26.9 PERCENT VD 29.5 LITER PPB 88.4 PERCENT Cl 66.4 LITER / HOUR HT 11 HOUR | HIV-1 GP120 PDB 5U7O (CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-626529 IN COMPLEX WITH HUMAN ANTIBODIES PGT122 AND 35O22 AT 3.8 ANGSTROM) LIGAND CODE = 83J (link to the list of PDB complexes) Download experimental 3D coordinates of 83J with added hydrogens | Envelope glycoprotein gp160 UNIPROT Q75760 env more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |