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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FINGOLIMOD (has an active metabolite)
| FINGOLIMOD | IMMUNOMODULATING | ORAL | F 93 PERCENT PPB 99.7 PERCENT SOLUBILITY FREELY SOLUBLE IN WATER | SPHINGOSINE 1-PHOSPHATE RECEPTOR (S1P1) | Sphingosine 1-phosphate receptor 1 UNIPROT P21453 S1PR1 -- Sphingosine 1-phosphate receptor 5 UNIPROT Q9H228 S1PR5 more at DrugCentral | EMA | |||
