PYRAZINAMIDE (has an active metabolite) | PYRAZINAMIDE | ATC J04AK01 ATC J04AM05
ANTIINFECTIVES TUBERCULOSTATIC ANTIFUNGAL ANTIBIOTIC ANTIBACTERIAL ANALOGUE OF NICOTINAMIDE | ORAL | Cmax 227.8 MICROMOLAR F 96.8 PERCENT VD 55.1 LITER (EQN) PPB 10 PERCENT Cl 3.82 LITER / HOUR HT 10 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | MYCOBACTERIAL PYRAZINAMIDASE (PNCA) PDB 5FPD (STRUCTURE OF HEAT SHOCK-RELATED 70KDA PROTEIN 2 WITH SMALL-MOLECULE LIGAND PYRAZINE-2-CARBOXAMIDE (AT513) IN AN ALTERNATE BINDING SITE.) LIGAND CODE = PZA (link to the list of PDB complexes) Download experimental 3D coordinates of PZA with added hydrogens | 3-oxoacyl-ACP synthase more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |