LAMIVUDINE (has an active metabolite) | LAMIVUDINE | ATC J05AF05 ATC J05AR02 ATC J05AR25 ATC J05AR16 ATC J05AR12 ATC J05AR13 ATC J05AR27 ATC J05AR24 ATC J05AR11 ATC J05AR28 ATC J05AR07 ATC J05AR01 ATC J05AR04 ATC J05AR05
ANTIINFECTIVES ANTIVIRAL ANTI-HIV AGENTS ANTI-HBV AGENTS NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) | ORAL | Cmax 15.1 MICROMOLAR (300 MILLIGRAM) PMID11605717 Tmax 1.3 HOUR F 87 PERCENT VD 84.5 LITER (65 KILOGRAM) PPB 36 PERCENT Cl 23.9 LITER / HOUR HT 6 HOUR SOLUBILITY OF 70 MILLIGRAM / MILLILITER IN WATER | REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) PDB 2NOA (THE STRUCTURE OF DEOXYCYTIDINE KINASE COMPLEXED WITH LAMIVUDINE AND ADP.) LIGAND CODE = 3TC (link to the list of PDB complexes) Download experimental 3D coordinates of 3TC with added hydrogens | Protein P UNIPROT Q9IF40 P -- Reverse transcriptase,RNaseH UNIPROT Q72547 pol more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |
M LAMIVUDINE (is an active metabolite) | LAMIVUDINE | ATC J05AF05 ATC J05AR02 ATC J05AR25 ATC J05AR16 ATC J05AR12 ATC J05AR13 ATC J05AR27 ATC J05AR24 ATC J05AR11 ATC J05AR28 ATC J05AR07 ATC J05AR01 ATC J05AR04 ATC J05AR05
ANTIINFECTIVES ANTIVIRAL ANTI-HIV AGENTS ANTI-HBV AGENTS NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS (NRTIS) | - | | REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) PDB 4K4H (TERNARY CRYSTAL STRUCTURES OF A HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)3TC-TP.) LIGAND CODE = 1RZ (link to the list of PDB complexes) Download experimental 3D coordinates of 1RZ with added hydrogens | Protein P UNIPROT Q9IF40 P -- Reverse transcriptase,RNaseH UNIPROT Q72547 pol more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |