Cheminformatic Tools and Databases for Pharmacology

session 62327 - Total of 3 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANDESARTAN (is an active metabolite)

CANDESARTAN


ATC C09CA06
ATC C09DB07
ATC C09DA06
ATC C09DX06

CARDIOVASCULAR
ANTIHYPERTENSIVE
CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST
CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II

-

F 15 PERCENT

VD 8.4 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 1.4 LITER / HOUR (65 KILOGRAM)

HT 9 HOUR

ANGIOTENSIN II RECEPTOR AT1

Type-1 angiotensin II receptor P30556 (AGTR1_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANDESARTAN CILEXETIL (has an active metabolite)

CANDESARTAN CILEXETIL


ATC C09CA06
ATC C09DB07
ATC C09DA06
ATC C09DX06

CARDIOVASCULAR
ANTIHYPERTENSIVE
HYDROLYZED TO CANDESARTAN DURING ABSORPTION FROM THE GASTROINTESTINAL TRACT
CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST
CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II

ORAL

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

ANGIOTENSIN II RECEPTOR AT1

Type-1 angiotensin II receptor P30556 (AGTR1_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

3 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANDESARTAN CILEXETIL (has an active metabolite)

CANDESARTAN CILEXETIL


ATC C09CA06
ATC C09DB07
ATC C09DA06
ATC C09DX06

CARDIOVASCULAR
ANTIHYPERTENSIVE
HYDROLYZED TO CANDESARTAN DURING ABSORPTION FROM THE GASTROINTESTINAL TRACT
CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST
CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II

ORAL

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

ANGIOTENSIN II RECEPTOR AT1

TYPE-1 ANGIOTENSIN II RECEPTOR ANTAGONIST CHEMBL227 ANGIOTENSIN II RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE ANGIOTENSIN RECEPTORANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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