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1	INN	Class	Route (list)	PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)	Primary Target and PDB code of Protein-Drug complex	Targets from DrugCentral	Links
CANDESARTAN (is an active metabolite)	CANDESARTAN	ATC C10BX19 ATC C09CA06 ATC C09DB07 ATC C09DA06 ATC C09DX06 CARDIOVASCULAR ANTIHYPERTENSIVE CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II	-	F 15 PERCENT VD 8.4 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 1.4 LITER / HOUR (65 KILOGRAM) HT 9 HOUR	ANGIOTENSIN II RECEPTOR AT1	Type-1 angiotensin II receptor UNIPROT P30556 AGTR1 more at DrugCentral	EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank
2	INN	Class	Route (list)	PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)	Primary Target and PDB code of Protein-Drug complex	Targets from DrugCentral	Links
CANDESARTAN CILEXETIL (has an active metabolite)	CANDESARTAN CILEXETIL	ATC C10BX19 ATC C09CA06 ATC C09DB07 ATC C09DA06 ATC C09DX06 CARDIOVASCULAR ANTIHYPERTENSIVE HYDROLYZED TO CANDESARTAN DURING ABSORPTION FROM THE GASTROINTESTINAL TRACT CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II	ORAL	SOLUBILITY PRACTICALLY INSOLUBLE IN WATER	ANGIOTENSIN II RECEPTOR AT1	Type-1 angiotensin II receptor UNIPROT P30556 AGTR1 more at DrugCentral	EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank