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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EPHEDRINE (has an active metabolite)
| EPHEDRINE | NATURAL MOLECULE (link)
RESPIRATORY | INTRAVENOUS | HT 6 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | ALPHA ADRENERGIC RECEPTOR BETA ADRENERGIC RECEPTOR | GPCR ADRB2_HUMAN AGONIST P07550 | ANSM (in French) | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NOREPINEPHRINE (is an active metabolite)
| NOREPINEPHRINE | NATURAL MOLECULE (link) CARDIOVASCULAR | INJECTION INTRAVENOUS | SOLUBILITY SPARINGLY SOLUBLE IN WATER | ADRENERGIC RECEPTORS PDB 3HCD (CRYSTAL STRUCTURE OF HPNMT IN COMPLEX WITH NORADRENALINE AND ADOHCY) LIGAND CODE = LNR (link to the list of PDB complexes) Download experimental 3D coordinates of LNR with added hydrogens | ADRENERGIC RECEPTOR AGONIST CHEMBL2331074 ADRENERGIC RECEPTOR P07550 BETA-2 ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTOR | ANSM (in French) | |||
