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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M PIMAVANSERIN (is an active metabolite)

PIMAVANSERIN


ATC N05AX17

NERVOUS SYSTEM
ANTIPSYCHOTIC
TREATMENT OF HALLUCINATIONS AND DELUSIONS ASSOCIATED WITH PARKINSON'S DISEASE PSYCHOSIS
INVERSE AGONIST / ANTAGONIST SEROTONIN 5-HT2A (KI = 0.087 NANOMOLAR) AND 5-HT2C (KI = 0.44 NANOMOLAR)
SIGMA 1 RECEPTOR (KI = 120 NANOMOLAR)

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HT 200 HOUR

5-HT2A RECEPTOR
5-HT2C RECEPTOR

GPCR 5HT2A_HUMAN INVERSE AGONIST P28223ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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