| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M DIAZEPAM (is an active metabolite) (has an active metabolite)
| DIAZEPAM | NERVOUS SYSTEM | - | VD 29.2 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 0.46 LITER / HOUR (65 KILOGRAM) HT 46 HOUR | GAMMA-AMINOBUTYRIC-ACID RECEPTOR | GABA A receptor alpha-5,beta-2,gamma-3 UNIPROT P31644 GABRA5 -- GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1 more at DrugCentral | EMA | |||
