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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M SOFOSBUVIR (is an active metabolite)
| SOFOSBUVIR |
ANTIINFECTIVES | - | Tmax 3 HOUR HT 27 HOUR | HEPATITIS C VIRUS (HCV) NUCLEOTIDE ANALOG NS5B POLYMERASE | HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE INHIBITOR CHEMBL5375 HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE Q8JXU8 NS5B PROTEIN HEPATITIS C VIRUS ENZYME TRANSFERASE | ANSM (in French) | |||
