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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M SOFOSBUVIR (is an active metabolite)

SOFOSBUVIR


ATC J05AX15
ATC J05AX65
ATC J05AP08
ATC J05AP51
ATC J05AP55
ATC J05AP56

ANTIINFECTIVES
TREATMENT OF CHRONIC HEPATITIS C (CHC) INFECTION
HEPATITIS C VIRUS (HCV) NUCLEOTIDE ANALOG NS5B POLYMERASE INHIBITOR

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Tmax 3 HOUR

HT 27 HOUR

HEPATITIS C VIRUS (HCV) NUCLEOTIDE ANALOG NS5B POLYMERASE

HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE INHIBITOR CHEMBL5375 HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE Q8JXU8 NS5B PROTEIN HEPATITIS C VIRUS ENZYME TRANSFERASEANSM (in French)

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