Cheminformatic Tools and Databases for Pharmacology

session 52421 - Total of 2 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M SAXAGLIPTIN (is an active metabolite)

SAXAGLIPTIN


ATC A10BD10
ATC A10BD25
ATC A10BH03
ATC A10BD21

ANTIDIABETIC
DIPEPTIDYL-PEPTIDASE IV INHIBITOR
HYPOGLYCEMIC AGENTS
TYPE 2 DIABETES MELLITUS
METABOLISM
METABOLITE OF SAXAGLIPTIN IS ONE-HALF AS POTENT AS SAXAGLIPTIN AS DPP4 INHIBITOR

-

Cmax 149 NANOMOLAR (5 MILLIGRAM)

VD 61 LITER (EQN)

PPB 0 PERCENT

Cl 13.8 LITER / HOUR

HT 3.1 HOUR

DIPEPTIDYL PEPTIDASE-4 (DPP-4)

Dipeptidyl peptidase 4 UNIPROT P27487 DPP4

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SAXAGLIPTIN (has an active metabolite)

SAXAGLIPTIN


ATC A10BD10
ATC A10BD25
ATC A10BH03
ATC A10BD21

ANTIDIABETIC
DIPEPTIDYL-PEPTIDASE IV INHIBITOR
HYPOGLYCEMIC AGENTS
TYPE 2 DIABETES MELLITUS
METABOLISM
METABOLITE OF SAXAGLIPTIN IS ONE-HALF AS POTENT AS SAXAGLIPTIN AS DPP4 INHIBITOR

ORAL

Cmax 76 NANOMOLAR (5 MILLIGRAM)

VD 49.7 LITER (EQN)

PPB 0 PERCENT

Cl 13.8 LITER / HOUR

HT 2.5 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

DIPEPTIDYL PEPTIDASE-4 (DPP-4)

Dipeptidyl peptidase 4 UNIPROT P27487 DPP4

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |