Cheminformatic Tools and Databases for Pharmacology

session 2311 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEXMETHYLPHENIDATE (is an active metabolite)

DEXMETHYLPHENIDATE
METHYLPHENIDATE


ATC N06BA04
ATC N06BA11

NERVOUS SYSTEM
CNS STIMULANT
ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD)
DOPAMINE REUPTAKE INHIBITORS
NOREPINEPHRINE REUPTAKE INHIBITOR
NERVOUS SYSTEM

ORAL TRANSDERMAL

Cmax 73 NANOMOLAR (20 MILLIGRAM)

Tmax 6.8 HOUR

F 23.5 PERCENT

VD 169 LITER (65 KILOGRAM)

PPB 15 PERCENT

Cl 33 LITER / HOUR

HT 3.2 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

SODIUM-DEPENDENT NORADRENALINE TRANSPORTER
SODIUM-DEPENDENT DOPAMINE TRANSPORTER
SODIUM-DEPENDENT SEROTONIN TRANSPORTER

NOREPINEPHRINE TRANSPORTER INHIBITOR CHEMBL222 NOREPINEPHRINE TRANSPORTER P23975 SODIUM-DEPENDENT NORADRENALINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |