Cheminformatic Tools and Databases for Pharmacology

session 10548 - Total of 2 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLORAZEPATE (has an active metabolite)

CLORAZEPATE


ATC N05BA05

NERVOUS SYSTEM
ANXIOLYTIC
ANTICONVULSANTS
GABA MODULATORS

ORAL

VD 13 LITER (65 KILOGRAM)

Cl 4.29 LITER / HOUR (65 KILOGRAM)

HT 2.4 HOUR

SOLUBILITY SOLUBLE IN WATER

GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT ALPHA-1 (GABA)

GABA-A RECEPTOR ANION CHANNEL POSITIVE ALLOSTERIC MODULATOR CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P14867 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M DIAZEPAM (is an active metabolite) (has an active metabolite)

DIAZEPAM


ATC N05BA01

NERVOUS SYSTEM
ANXIOLYTIC
BENZODIAZEPINES
MUSCLE RELAXANTS
SEDATIVE

-

VD 29.2 LITER (65 KILOGRAM)

PPB 97 PERCENT

Cl 0.46 LITER / HOUR (65 KILOGRAM)

HT 46 HOUR

GAMMA-AMINOBUTYRIC-ACID RECEPTOR

GABA-A RECEPTOR ANION CHANNEL POSITIVE ALLOSTERIC MODULATOR CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P14867 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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