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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NOREPINEPHRINE (is an active metabolite)
| NOREPINEPHRINE | NATURAL MOLECULE (link) CARDIOVASCULAR | INJECTION INTRAVENOUS | SOLUBILITY SPARINGLY SOLUBLE IN WATER | ADRENERGIC RECEPTORS PDB 3HCD (CRYSTAL STRUCTURE OF HPNMT IN COMPLEX WITH NORADRENALINE AND ADOHCY) LIGAND CODE = LNR (link to the list of PDB complexes) Download experimental 3D coordinates of LNR with added hydrogens | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2 more at DrugCentral | EMA | |||
