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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M TEMOZOLOMIDE (is an active metabolite)
| TEMOZOLOMIDE | ANTINEOPLASTIC | - | Cmax 1.64 MICROMOLAR | DNA | Unknown more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TEMOZOLOMIDE (has an active metabolite)
| TEMOZOLOMIDE | ANTINEOPLASTIC | ORAL INTRAVENOUS | Cmax 37.6 MICROMOLAR Tmax 1 HOUR F 100 PERCENT VD 26 LITER PPB 95 PERCENT Cl 8.8 LITER / HOUR HT 1.8 HOUR | DNA | Unknown more at DrugCentral | EMA | |||
