| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| QUINAPRIL (has an active metabolite)
| QUINAPRIL | CARDIOVASCULAR | ORAL | Tmax 1 HOUR F 60 PERCENT PPB 97 PERCENT SOLUBILITY FREELY SOLUBLE IN WATER | ANGIOTENSIN-CONVERTING ENZYME | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR CHEMBL1808 ANGIOTENSIN-CONVERTING ENZYME P12821 ANGIOTENSIN-CONVERTING ENZYME HOMO SAPIENS ENZYME PROTEASE METALLO MAE M2 | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| QUINAPRILAT (is an active metabolite)
| QUINAPRILAT | CARDIOVASCULAR | - | Tmax 2 HOUR VD 8.4 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 3.6 LITER / HOUR (65 KILOGRAM) HT 2 HOUR | ANGIOTENSIN-CONVERTING ENZYME | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR CHEMBL1808 ANGIOTENSIN-CONVERTING ENZYME P12821 ANGIOTENSIN-CONVERTING ENZYME HOMO SAPIENS ENZYME PROTEASE METALLO MAE M2 | EMA | |||
