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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MIDODRINE (has an active metabolite)
| MIDODRINE | CARDIOVASCULAR | ORAL | Tmax 0.5 HOUR F 100 PERCENT PPB 0 PERCENT HT 0.4 HOUR SOLUBILITY SOLUBLE IN WATER | ALPHA ADRENERGIC RECEPTOR | Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M MIDODRINE (is an active metabolite)
| MIDODRINE | CARDIOVASCULAR | - | Tmax 1.5 HOUR F 93 PERCENT PPB 0 PERCENT HT 3.5 HOUR SOLUBILITY SOLUBLE IN WATER | ALPHA-1A ADRENERGIC RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR | Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A more at DrugCentral | EMA | |||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M MIDODRINE (is an active metabolite)
| MIDODRINE | CARDIOVASCULAR | - | Tmax 1.5 HOUR F 93 PERCENT PPB 0 PERCENT HT 3.5 HOUR SOLUBILITY SOLUBLE IN WATER | ALPHA-1A ADRENERGIC RECEPTOR ALPHA-1B ADRENERGIC RECEPTOR | Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A more at DrugCentral | EMA | |||
