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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BECLOMETHASONE DIPROPIONATE (has an active metabolite)
| BECLOMETHASONE DIPROPIONATE |
METABOLISM | INHALATION NASAL | Cmax 169 PICOMOLAR Tmax 0.5 HOUR VD 20 LITER PPB 87 PERCENT Cl 150 LITER / HOUR HT 0.5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M BECLOMETHASONE DIPROPIONATE (is an active metabolite)
| BECLOMETHASONE DIPROPIONATE |
METABOLISM | - | Cmax 16 NANOMOLAR Tmax 0.7 HOUR F 43 PERCENT VD 424 LITER PPB 87 PERCENT Cl 120 LITER / HOUR HT 2.7 HOUR | GLUCOCORTICOID RECEPTOR | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
