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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FEXINIDAZOLE (has an active metabolite)
| FEXINIDAZOLE | ANTIPARASITIC | ORAL | Cmax 2.9 MICROMOLAR Tmax 4 HOUR VD 3222 LITER PPB 98 PERCENT Cl 161 LITER / HOUR HT 15 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | More at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M FEXINIDAZOLE (is an active metabolite)
| FEXINIDAZOLE | ANTIPARASITIC | - | Cmax 27 MICROMOLAR Tmax 4 HOUR PPB 41 PERCENT HT 16 HOUR | More at DrugCentral | EMA | ||||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M FEXINIDAZOLE (is an active metabolite)
| FEXINIDAZOLE | ANTIPARASITIC | - | Cmax 63 MICROMOLAR Tmax 6 HOUR PPB 57 PERCENT HT 23 HOUR | More at DrugCentral | EMA | ||||
