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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MELPHALAN (is an active metabolite)
| MELPHALAN | ANTINEOPLASTIC | ORAL INJECTION INTRAVENOUS | Cmax 695 NANOMOLAR Tmax 1 HOUR F 74 PERCENT VD 32.5 LITER (65 KILOGRAM) PPB 72 PERCENT Cl 27.3 LITER / HOUR (65 KILOGRAM) HT 1.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | DNA | DNA INHIBITOR CHEMBL2311221 DNA HOMO SAPIENS | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MELPHALAN FLUFENAMIDE DISCONTINUED (has an active metabolite)
| MELPHALAN FLUFENAMIDE | ANTINEOPLASTIC | INTRAVENOUS | Tmax 0.5 HOUR VD 35 LITER Cl 692 LITER / HOUR HT 0.035 HOUR SOLUBILITY SPARSELY SOLUBLE IN AQUEOUS SOLUTIONS | DNA | Unknown - more at DrugCentral | EMA | |||
