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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CANNABIDIOL (has an active metabolite)
| CANNABIDIOL | NATURAL MOLECULE (link) NERVOUS SYSTEM | ORAL | Tmax 3.75 HOUR VD 31906 LITER PPB 94 PERCENT Cl 1111 LITER / HOUR HT 58.5 HOUR SOLUBILITY INSOLUBLE IN WATER | CANNABINOID RECEPTOR PDB 6U8A (CBD-BOUND FULL-LENGTH RAT TRPV2 IN NANODISCS, STATE 1) LIGAND CODE = P0T (link to the list of PDB complexes) Download experimental 3D coordinates of P0T with added hydrogens | G-protein coupled receptor 55 Q9Y2T6 | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M CANNABIDIOL (is an active metabolite)
| CANNABIDIOL | NERVOUS SYSTEM | - | CANNABINOID RECEPTOR | G-protein coupled receptor 55 Q9Y2T6 | EMA | ||||
