| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| METHSUXIMIDE (has an active metabolite)
| METHSUXIMIDE | NERVOUS SYSTEM | ORAL | HT 1.4 HOUR | Voltage-gated T-type calcium channel UNIPROT O43497 CACNA1G more at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M METHSUXIMIDE (is an active metabolite)
| METHSUXIMIDE | NERVOUS SYSTEM | - | HT 38 HOUR | Voltage-gated T-type calcium channel UNIPROT O43497 CACNA1G more at DrugCentral | EMA | ||||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M METHSUXIMIDE (is an active metabolite)
| METHSUXIMIDE | NERVOUS SYSTEM | - | HT 38 HOUR | Voltage-gated T-type calcium channel UNIPROT O43497 CACNA1G more at DrugCentral | EMA | ||||
