| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M NETARSUDIL (is an active metabolite)
| NETARSUDIL | SENSORY | - | RHO KINASE | Rho-associated protein kinase 2 UNIPROT O75116 ROCK2 more at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| NETARSUDIL (has an active metabolite)
| NETARSUDIL | SENSORY | OPHTHALMIC | SOLUBILITY FREELY SOLUBLE IN WATER | RHO KINASE | Rho-associated protein kinase 2 UNIPROT O75116 ROCK2 more at DrugCentral | EMA | |||
