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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PHENDIMETRAZINE (has an active metabolite)
| PHENDIMETRAZINE | METABOLISM | ORAL | HT 3.7 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | NORADRENALINE TRANSPORTER DOPAMINE TRANSPORTER | Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2 -- Sodium-dependent dopamine transporter UNIPROT Q01959 SLC6A3 more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PHENMETRAZINE DISCONTINUED (is an active metabolite)
| PHENMETRAZINE | NERVOUS SYSTEM | ORAL | NORADRENALINE TRANSPORTER DOPAMINE TRANSPORTER | Sodium-dependent noradrenaline transporter UNIPROT P23975 SLC6A2 -- Sodium-dependent dopamine transporter UNIPROT Q01959 SLC6A3 more at DrugCentral | EMA | ||||
