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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIBOFLAVIN (is an active metabolite)
| RIBOFLAVIN | NATURAL MOLECULE (link) METABOLISM | INJECTION INTRAVENOUS | Cmax 1.2 MICROMOLAR (PMID8604671) Tmax 2 HOUR VD 39.6 LITER (65 KILOGRAM) PPB 35.5 PERCENT Cl 29.3 LITER / HOUR HT 0.93 HOUR (EQN) | FLAVOKINASE FLAVIN ADENIN DINUCLEOTIDE (FAD) SYNTHASE PDB 2CCB (COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS) LIGAND CODE = RBF (link to the list of PDB complexes) Download experimental 3D coordinates of RBF with added hydrogens | Riboflavin kinase K UNIPROT Q969G6 RFK more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RIBOFLAVIN PHOSPHATE (has an active metabolite)
| RIBOFLAVIN PHOSPHATE | NATURAL MOLECULE (link) VITAMIN B2 | INJECTION INTRAVENOUS OPHTHALMIC | SOLUBILITY WATER SOLUBLE VITAMIN | CYTOCHROME B2 MITOCHONDRIAL PDB 6CNY (2.3 ANGSTROM STRUCTURE OF PHOSPHODIESTERASE TREATED VIVID (COMPLEX WITH FMN)) LIGAND CODE = FMN (link to the list of PDB complexes) Download experimental 3D coordinates of FMN with added hydrogens | Unknown more at DrugCentral | EMA | |||
