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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TEDIZOLID (is an active metabolite)
| TEDIZOLID | ANTIINFECTIVES | - | Cmax 8.1 MICROMOLAR Tmax 1.2 HOUR F 91 PERCENT VD 73.5 LITER PPB 80 PERCENT Cl 5.9 LITER / HOUR HT 12 HOUR | RIBOSOME 50S SUBUNIT PDB 6WRS (STRUCTURE OF THE 50S SUBUNIT OF THE RIBOSOME FROM METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN COMPLEX WITH THE ANTIBIOTIC, TEDIZOLID) LIGAND CODE = U7V (link to the list of PDB complexes) Download experimental 3D coordinates of U7V with added hydrogens | Unknown more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TEDIZOLID PHOSPHATE (has an active metabolite)
| TEDIZOLID PHOSPHATE | ANTIINFECTIVES | ORAL INTRAVENOUS | RIBOSOME 50S SUBUNIT | Unknown more at DrugCentral | EMA | ||||
