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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLUDARABINE (is an active metabolite) (has an active metabolite)
| FLUDARABINE | ANTINEOPLASTIC | - | Tmax 1.5 HOUR F 57 PERCENT VD 143 LITER (65 KILOGRAM) PPB 24 PERCENT Cl 12.4 LITER / HOUR (65 KILOGRAM) HT 20 HOUR | DEOXYCYTIDINE KINASE | DNA POLYMERASE (ALPHA/DELTA/EPSILON) INHIBITOR CHEMBL2363042 DNA POLYMERASE (ALPHA/DELTA/EPSILON) P09884 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT HOMO SAPIENS ENZYME TRANSFERASE | EMA | |||
