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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M LAMIVUDINE (is an active metabolite)
| LAMIVUDINE |
ANTIINFECTIVES | - | REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN) PDB 4K4H (TERNARY CRYSTAL STRUCTURES OF A HUMAN DNA POLYMERASE LAMBDA IN COMPLEX WITH DNA AND (-)3TC-TP.) LIGAND CODE = 1RZ (link to the list of PDB complexes) Download experimental 3D coordinates of 1RZ with added hydrogens | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE INHIBITOR CHEMBL247 HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE Q72547 REVERSE TRANSCRIPTASE/RNASEH HUMAN IMMUNODEFICIENCY VIRUS 1 ENZYME HYDROLASE | EMA | ||||
