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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M PRASUGREL (is an active metabolite)
| PRASUGREL | BLOOD | - | Tmax 0.5 HOUR F 79 PERCENT VD 56 LITER PPB 98 PERCENT Cl 139 LITER / HOUR HT 7 HOUR | P2Y12 ADP RECEPTOR | P2Y purinoceptor 12 UNIPROT Q9H244 P2RY12 more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRASUGREL (has an active metabolite)
| PRASUGREL | BLOOD | ORAL | F 79 PERCENT SOLUBILITY PRACTICALLY INSOLUBLE AT PH 6 TO 7.5 | P2Y12 ADP RECEPTOR | P2Y purinoceptor 12 UNIPROT Q9H244 P2RY12 more at DrugCentral | EMA | |||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRASUGREL (has an active metabolite)
| PRASUGREL | BLOOD | ORAL | F 79 PERCENT SOLUBILITY PRACTICALLY INSOLUBLE AT PH 6 TO 7.5 | P2Y12 ADP RECEPTOR | P2Y purinoceptor 12 UNIPROT Q9H244 P2RY12 more at DrugCentral | EMA | |||
