| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FINGOLIMOD (has an active metabolite)
| FINGOLIMOD | IMMUNOMODULATING | ORAL | F 93 PERCENT PPB 99.7 PERCENT SOLUBILITY FREELY SOLUBLE IN WATER | SPHINGOSINE 1-PHOSPHATE RECEPTOR (S1P1) | SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONIST CHEMBL2363041 SPHINGOSINE 1-PHOSPHATE RECEPTOR O95136 SPHINGOSINE 1-PHOSPHATE RECEPTOR 2 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL LIPID-LIKE LIGAND RECEPTOR EDG RECEPTOR | EMA | |||
