| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FESOTERODINE (has an active metabolite)
| FESOTERODINE | ANTISPASMODICS | ORAL | SOLUBILITY FREELY SOLUBLE IN WATER | MUSCARINIC RECEPTOR ANTAGONIST | Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M FESOTERODINE (is an active metabolite)
| FESOTERODINE | ANTISPASMODICS | - | Cmax 11.6 NANOMOLAR (8 MILLIGRAM) Tmax 1.8 HOUR F 52 PERCENT VD 169 LITER PPB 50 PERCENT Cl 13.6 LITER / HOUR (EQN) HT 8.59 HOUR | MUSCARINIC RECEPTOR | Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
