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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PRASTERONE (has an active metabolite)
| PRASTERONE |
HORMONES | VAGINAL | Cmax 15 NANOMOLAR SOLUBILITY INSOLUBLE IN WATER | HYDROXYSTEROID DEHYDROGENASES 5ALPHA-REDUCTASES AROMATASES PDB 1Q22 (CRYSTAL STRUCTURE OF HUMAN CHOLESTEROL SULFOTRANSFERASE (SULT2B1B) IN THE PRESENCE OF DHEA AND PAP) LIGAND CODE = AND (link to the list of PDB complexes) Download experimental 3D coordinates of AND with added hydrogens | Unknown more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TESTOSTERONE (is an active metabolite)
| TESTOSTERONE | NATURAL MOLECULE (link) GENITO | TRANSDERMAL BUCCAL IMPLANTATION INJECTION NASAL | Cmax 31.4 NANOMOLAR Tmax 8 HOUR VD 65 LITER (65 KILOGRAM) PPB 98 PERCENT Cl 62.4 LITER / HOUR (65 KILOGRAM) HT 192 HOUR | ANDROGEN RECEPTOR PDB 1AFS (RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE) LIGAND CODE = TES (link to the list of PDB complexes) Download experimental 3D coordinates of TES with added hydrogens | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | |||
| 3 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TESTOSTERONE CYPIONATE (has an active metabolite)
| TESTOSTERONE CYPIONATE | HORMONES | INJECTION INTRAMUSCULAR | SOLUBILITY INSOLUBLE IN WATER | ANDROGEN RECEPTOR | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | |||
| 4 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TESTOSTERONE ENANTHATE (has an active metabolite)
| TESTOSTERONE ENANTHATE | HORMONES | INJECTION SUBCUTANEOUS | SOLUBILITY INSOLUBLE IN WATER | ANDROGEN RECEPTOR | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | |||
| 5 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TESTOSTERONE PROPIONATE DISCONTINUED (has an active metabolite)
| TESTOSTERONE PROPIONATE | GENITO | INJECTION | ANDROGEN RECEPTOR | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | ||||
| 6 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TESTOSTERONE UNDECANOATE (has an active metabolite)
| TESTOSTERONE UNDECANOATE | GENITO | INTRAMUSCULAR ORAL | SOLUBILITY INSOLUBLE IN WATER | ANDROGEN RECEPTOR | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | |||
