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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| UNOPROSTONE (is an active metabolite)
| UNOPROSTONE | SENSORY | - | Cmax 3.92 NANOMOLAR HT 0.23 HOUR | BK (KCA1.1) CHANNEL (PMID26277265) | Unknown - more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| UNOPROSTONE ISOPROPYL DISCONTINUED (has an active metabolite)
| UNOPROSTONE ISOPROPYL | SENSORY | OPHTHALMIC | SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | BK (KCA1.1) CHANNEL (PMID26277265) | Unknown - more at DrugCentral | EMA | |||
