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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ESTRAMUSTINE (is an active metabolite)
| ESTRAMUSTINE | ANTINEOPLASTIC | - | HT 13.6 HOUR | ESTROGEN RECEPTOR | DNA INHIBITOR CHEMBL2311221 DNA Q92731 ESTROGEN RECEPTOR BETA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3A NR3A2 | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ESTRAMUSTINE PHOSPHATE (has an active metabolite)
| ESTRAMUSTINE PHOSPHATE | ANTINEOPLASTIC | ORAL | Tmax 2 HOUR F 70 PERCENT VD 7.8 LITER (65 KILOGRAM) Cl 3.6 LITER / HOUR (65 KILOGRAM) HT 2.4 HOUR SOLUBILITY READILY SOLUBLE IN WATER | ESTROGEN RECEPTOR | DNA INHIBITOR CHEMBL2311221 DNA Q92731 ESTROGEN RECEPTOR BETA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3A NR3A2 | EMA | |||
