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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FLUPHENAZINE (is an active metabolite)

FLUPHENAZINE


ATC N05AB02

NERVOUS SYSTEM
ANTIPSYCHOTICS
DOPAMINE ANTAGONISTS (PMID24150997)
PHENOTHIAZINES

ORAL INJECTION

HT 16.4 HOUR

D(1) DOPAMINE RECEPTOR
D(2) DOPAMINE RECEPTOR

D(2) dopamine receptor UNIPROT P14416 DRD2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank

2 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FLUPHENAZINE DECANOATE (has an active metabolite)

FLUPHENAZINE DECANOATE


ATC N05AB02

NERVOUS SYSTEM
ANTIPSYCHOTIC
PHENOTHIAZINE DERIVATIVE
ANTAGONIST
HYDROLYSED BY ESTERASES

INJECTION D2 DOPAMINE RECEPTOR

D(2) dopamine receptor UNIPROT P14416 DRD2 -- D(2) dopamine receptor UNIPROT P14416 DRD2

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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