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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFAMANDOLE (is an active metabolite)
| CEFAMANDOLE | ANTIINFECTIVES | - | VD 10.4 LITER (65 KILOGRAM) PPB 75 PERCENT Cl 14 LITER / HOUR (65 KILOGRAM) HT 0.75 HOUR | PENICILLIN-BINDING PROTEINS 1A/1B PDB 3NY4 (CRYSTAL STRUCTURE OF BLAC-K73A BOUND WITH CEFAMANDOLE) LIGAND CODE = SMX (link to the list of PDB complexes) Download experimental 3D coordinates of SMX with added hydrogens | Unknown more at DrugCentral | EMA | |||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CEFAMANDOLE NAFATE DISCONTINUED (has an active metabolite)
| CEFAMANDOLE NAFATE | ANTIINFECTIVES | INJECTION | PENICILLIN-BINDING PROTEINS 1A/1B | Bacterial penicillin-binding protein UNIPROT P02918 mrcA more at DrugCentral | EMA | ||||
