| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TETRACYCLINE
| TETRACYCLINE |
ANTIINFECTIVES | ORAL OPHTHALMIC INJECTION TOPICAL PERIODONTAL | Cmax 1.68 MICROMOLAR Tmax 3.3 HOUR VD 78 LITER (65 KILOGRAM) PPB 22 PERCENT Cl 5.8 LITER / HOUR (65 KILOGRAM) HT 9.4 HOUR | 30S RIBOSOMAL PROTEIN PDB 2HDN (TRYPSIN-MODIFIED ELONGATION FACTOR TU IN COMPLEX WITH TETRACYCLINE AT 2.8 ANGSTROM RESOLUTION) LIGAND CODE = TAC (link to the list of PDB complexes) Download experimental 3D coordinates of TAC with added hydrogens | Unknown more at DrugCentral | EMA | |||
