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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PENICILLIN V

PENICILLIN V


ATC J01CE02

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
PENICILLINS

ORAL

VD 26.6 LITER (65 KILOGRAM)

PPB 80 PERCENT

Cl 26.5 LITER / HOUR (65 KILOGRAM)

HT 0.84 HOUR

BETA-LACTAMASE
PENICILLIN-BINDING PROTEINS 1A/1B

PDB 2Z71 (STRUCTURE OF TRUNCATED MUTANT CYS1GLY OF PENICILLIN V ACYLASE FROM BACILLUS SPHAERICUS CO-CRYSTALLIZED WITH PENICILLIN V)

LIGAND CODE = PNV (link to the list of PDB complexes)

Download experimental 3D coordinates of PNV with added hydrogens

Bacterial penicillin-binding protein UNIPROT P02918 mrcA

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
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Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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