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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PHENYLEPHRINE

PHENYLEPHRINE


ATC C01CA06
ATC C05AX06
ATC R01AA04
ATC R01AB01
ATC R01BA03
ATC S01FB01
ATC S01GA05
ATC S01FB51
ATC R01BA53
ATC S01GA55

CARDIOVASCULAR
SELECTIVE ADRENERGIC ALPHA-1 AGONISTS
CARDIOTONIC AGENTS
MYDRIATICS
NASAL DECONGESTANTS
SYMPATHOMIMETICS
VASOCONSTRICTOR AGENTS

OPHTHALMIC ORAL INHALATION INTRAVENOUS IRRIGATION

Cmax 5.2 MILLIMOLAR (10 MILLIGRAM , PMID25475358)

Tmax 0.76 HOUR

VD 340 LITER

Cl 2 LITER / HOUR (PMID7056280)

HT 1.35 HOUR (PMID25475358)

ADRENERGIC ALPHA-1 RECEPTOR

Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A -- Alpha-1D adrenergic receptor UNIPROT P25100 ADRA1D

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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