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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GRISEOFULVIN
| GRISEOFULVIN | NATURAL MOLECULE (link) DERMATOLOGICALS | ORAL | Cmax 1.9 MICROMOLAR (250 MILLIGRAM ORAL) Tmax 4 HOUR VD 45.5 LITER (65 KILOGRAM) PPB 80 PERCENT HT 16.5 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | Tubulin UNIPROT F2SG63 more at DrugCentral | EMA | ||||
