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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| IXABEPILONE
| IXABEPILONE | ANTINEOPLASTIC | INTRAVENOUS | Cmax 0.49 MICROMOLAR Tmax 3 HOUR VD 1000 LITER PPB 72 PERCENT Cl 39 LITER / HOUR (65 KILOGRAM) HT 52 HOUR | BETA TUBULIN PDB 7DAF (IXA IN COMPLEX WITH TUBULIN) LIGAND CODE = GZX (link to the list of PDB complexes) Download experimental 3D coordinates of GZX with added hydrogens | Tubulin beta UNIPROT P07437 TUBB more at DrugCentral | EMA | |||
