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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EPINASTINE
| EPINASTINE | RESPIRATORY SYSTEM | OPHTHALMIC | Cmax 0.16 NANOMOLAR VD 969 LITER (EQN) PPB 64 PERCENT Cl 56 LITER / HOUR HT 12 HOUR | HISTAMINE H1 RECEPTOR 5-HYDROXYTRYPTAMINE 2A RECEPTOR ALPHA-1A ADRENERGIC RECEPTOR ALPHA-2 ADRENERGIC RECEPTOR | Histamine H1 receptor UNIPROT P35367 HRH1 more at DrugCentral | EMA | |||
