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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ACAMPROSATE
| ACAMPROSATE | NERVOUS SYSTEM | ORAL | Tmax 5.5 HOUR F 11 PERCENT VD 90.5 LITER PPB 0 PERCENT Cl 2.3 LITER / HOUR (EQN) HT 26.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | GABA-A receptor alpha-1,beta-3,gamma-2 UNIPROT P14867 GABRA1 -- Glutamate NMDA receptor UNIPROT O15399 GRIN2D more at DrugCentral | EMA | ||||
