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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GATIFLOXACIN
| GATIFLOXACIN | ANTIINFECTIVES | OPHTHALMIC | Cmax 11.2 MICROMOLAR Tmax 1.5 HOUR F 96 PERCENT VD 104 LITER (65 KILOGRAM) PPB 20 PERCENT Cl 11.9 LITER / HOUR HT 7.1 HOUR SOLUBILITY MAXIMUM AQUEOUS SOLUBILITY (40-60 MILLIGRAM / MILLILITER) OCCURS AT A PH RANGE OF 2 TO 5 | DNA GYRASE TOPOISOMERASE 4 | DNA topoisomerase 4 UNIPROT P72525 parC -- DNA gyrase UNIPROT P0A4L9 gyrB more at DrugCentral | EMA | |||
