| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DUTASTERIDE
| DUTASTERIDE | GENITO | ORAL | Cmax 6.4 NANOMOLAR Tmax 2.5 HOUR F 60 PERCENT VD 400 LITER PPB 99 PERCENT Cl 0.33 LITER / HOUR (EQN) HT 840 HOUR SOLUBILITY INSOLUBLE IN WATER | 5 ALPHA-REDUCTASE | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 UNIPROT P31213 SRD5A2 -- 3-oxo-5-alpha-steroid 4-dehydrogenase 1 UNIPROT P18405 SRD5A1 more at DrugCentral | EMA | |||
