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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VALGANCICLOVIR (has an active metabolite)
| VALGANCICLOVIR | ANTIINFECTIVE | ORAL | F 60 PERCENT SOLUBILITY SOLUBILITY OF 70 MILLIGRAM / MILLILITER IN WATER AT 25 DEGREE CELSIUS AT A PH 7.0 | PDB 6GS4 (CRYSTAL STRUCTURE OF PEPTIDE TRANSPORTER DTPA-NANOBODY IN COMPLEX WITH VALGANCICLOVIR) LIGAND CODE = F9E (link to the list of PDB complexes) Download experimental 3D coordinates of F9E with added hydrogens | DNA polymerase catalytic subunit UNIPROT P04293 more at DrugCentral | EMA | |||
