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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ALFUZOSIN

ALFUZOSIN


ATC G04CA01
ATC G04CA51

GENITO
ANTIHYPERTENSIVE
ALPHA ADRENERGIC ANTAGONISTS
TREATMENT OF BENIGN PROSTATIC HYPERPLASIA

ORAL

Cmax 34.9 NANOMOLAR

Tmax 8 HOUR

F 49 PERCENT

VD 208 LITER (65 KILOGRAM)

PPB 86 PERCENT

Cl 23 LITER / HOUR (65 KILOGRAM)

HT 10 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

ALPHA ADRENERGIC RECEPTOR

Alpha-1A adrenergic receptor UNIPROT P35348 ADRA1A -- Alpha-1D adrenergic receptor UNIPROT P25100 ADRA1D

more at DrugCentral

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