Cheminformatic Tools and Databases for Pharmacology

session 6833 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NATEGLINIDE

NATEGLINIDE


ATC A10BX03

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
MEGLITINIDES
BINDS ATP-SENSITIVE POTASSIUM (K+ATP) CHANNEL ON PANCREATIC BETA-CELLS

ORAL

Tmax 1 HOUR

F 73 PERCENT

VD 10 LITER

PPB 98 PERCENT

Cl 7 LITER / HOUR

HT 1.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL

Sulfonylurea receptor 1, Kir6.2 UNIPROT Q09428 ABCC8

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |